I MALE BREAST CANCER
It comes as a surprise to many that men can get breast cancer – a particularly unpleasant surprise both to the men that are diagnosed with it and their families. One in 1,000 men develop the disease at some point in their lives, which accounts for around 200 cases a year in the UK. Male breast cancer is governed by the same hormonal influences as female breast cancers and there are many similarities between male breast cancer and breast cancer in post-menopausal women. Incidence is more likely with advancing years, with most men diagnosed aged sixty-plus, and the condition being extremely rare under the age of thirty. As with female breast cancer, the incidence is lower in Japan and other Far Eastern countries, and more common in the UK and USA. There is a high incidence of male breast cancer in some African countries where the frequency of liver infections is high. Liver problems reduce the ability of the body to process oestrogens correctly.
Men with Klinefelter’s syndrome, which affects one in 300 men who have an XXY chromosome pattern instead of the normal male XY chromosomes, have hormonal anomalies, and the incidence rate is similar to that of women. A condition known as gynaecomastia is an excess of breast tissue in men, and is associated with male breast cancer in up to 40 per cent of cases. Chest radiation exposure, testicular injury or inflammation, undescended testes, a history of using drugs which raise prolactin levels, a family history of breast cancer (male and female) and obesity are all added risk factors.
As there is less breast tissue in men, lumps are usually found at an earlier stage than for women. However, the lack of intervening tissue also means that spread to the lymph glands happens at an earlier stage. Men are also less likely to report a lump in the breast area than women, and a delay of eighteen to twenty-four months is common.
Bloody nipple discharge is present in about 80 per cent of all male breast cancer cases.
Treatment for men is similar to that for women. This includes surgery, which may also require skin grafts, as there is less ‘surplus’ skin to work with, and sometimes Tamoxifen. There is some evidence that men do not tolerate Tamoxifen as well as women, and in one study one in five men stopped treatment because of unpleasant side-effects, compared to one in twenty women.
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